From Brad Margus

Drug Repurposing Screen for A-T Reaches Important Milestone

Aug 11, 2022 Comments Off on Drug Repurposing Screen for A-T Reaches Important Milestone
Apr 13 @ 9:26 am

Charles River Lab, a drug development services company collaborating with the A-T Children’s Project, has succeeded in developing a laboratory test or “assay” to rapidly evaluate thousands of approved drugs to learn if some of them can be repurposed for A-T. Because drugs emerging from the screening process with promising…

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Help Accelerate A-T Research

Dec 31, 2021 Comments Off on Help Accelerate A-T Research
Apr 13 @ 9:26 am

As we head into 2022, research to find treatments for ataxia-telangiectasia (A-T) is moving more swiftly than ever. Please help us maintain momentum by making a year-end donation. Researchers at Boston Children’s Hospital are now treating a little girl with A-T using antisense oligonucleotide (ASO) gene therapy and will soon be expanding…

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Large-Scale Drug Screening for A-T

Aug 6, 2021 Comments Off on Large-Scale Drug Screening for A-T
Apr 13 @ 9:26 am

Dear Friends, I hope you and your families are remaining safe as Covid continues to throw new challenges at us. While the pandemic has made funding and operating the A-T Children’s Project vastly more difficult, we’re continuing to drive forward innovative research, knowing that our kids will keep deteriorating a…

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A Biomarker to Track Brain Cell Death in A-T Kids

Jun 4, 2020 Comments Off on A Biomarker to Track Brain Cell Death in A-T Kids
Apr 13 @ 9:26 am

Hi everyone, I hope you and your families are continuing to stay safe during the pandemic. Over the past year, you’ve heard me talk a lot about testing an approach called antisense oligonucleotide (ASO) gene therapy in a little girl with   A-T. She has continued to receive regular injections, and…

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A-T ASO Gene Therapy Trial Continues!

Apr 17, 2020 Comments Off on A-T ASO Gene Therapy Trial Continues!
Apr 13 @ 9:26 am

Hi everyone, I hope you and your family are doing well and keeping safe. As much as the COVID-19 pandemic has changed our world, I wanted to let you know that our ASO gene therapy trial for A-T – that you helped make possible – has not stopped. It continues…

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Update on Testing ASO Gene Therapy in A-T Kids

Mar 25, 2019 Comments Off on Update on Testing ASO Gene Therapy in A-T Kids
Apr 13 @ 9:26 am

As this historic milestone approaches, we can’t help but feel a renewed sense of urgency to reach our goal.  And, we never forget for even a moment that this project would not be happening without the wonderful support we’ve received from you. More soon, Brad Margus Founder

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