Research Updates

California Researcher Continues Development of a Cell Model for A-T

Dec 1, 2011 Comments Off on California Researcher Continues Development of a Cell Model for A-T
Nov 5 @ 4:01 am

The A-T Children’s Project has granted funding for Yang Xu, PhD from the University of California, San Diego to continue development of a stem cell-based model for A-T. This type of “disease-in-a-dish” model can be used to screen hundreds of thousands of compounds for their ability to diminish or reverse…

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Young LSU Investigator Receives Post Doctoral Fellowship Award

Nov 10, 2011 Comments Off on Young LSU Investigator Receives Post Doctoral Fellowship Award
Nov 5 @ 4:01 am

Benjamin Siddoway, PhD from the Louisiana State University (LSU) Health Sciences Center is the first recipient of the A-T Children’s Project’s Post Doctoral Fellowship Award for his grant entitled “Addressing neurological dysfunction in A-T: Investigation into novel, physiologic ATM activation in neurons and ATM-PP1 signaling in reorganization and refinement of…

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Two New Research Projects to Focus on Cell Death and Consequences in the Brain

Oct 1, 2011 Comments Off on Two New Research Projects to Focus on Cell Death and Consequences in the Brain
Nov 5 @ 4:01 am

The A-T Children’s Project is funding two new research grants that may provide insights regarding brain function in A-T. The Florida-based Wobbly Feet Foundation has agreed to co-fund part of each grant in an on-going partnership to accelerate A-T research. Research for the first grant, entitled “Linking neurodegeneration to protein…

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Examining the Benefits of Inspiratory Muscle Strength Training

Sep 20, 2011 Comments Off on Examining the Benefits of Inspiratory Muscle Strength Training
Nov 5 @ 4:01 am

The A-T Children’s Project and the A-T Society in the United Kingdom have jointly awarded a grant to Emma Ross PhD, from the University of Brighton in England, entitled “Inspiratory muscle training in patients with Ataxia-Telangiectasia.” Lung disease is a frequent and often serious problem in patients with A-T. A…

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Johns Hopkins Hospital: Ground-breaking Paper Helps Doctors Manage Lung Problems in A-T

Jul 25, 2011 Comments Off on Johns Hopkins Hospital: Ground-breaking Paper Helps Doctors Manage Lung Problems in A-T
Nov 5 @ 4:01 am

Lung problems cause sickness and death in many patients with ataxia-telangiectasia (A-T). However, a lack of information from following A-T patients’ lung disease over time has limited doctors’ knowledge of these critical problems. With the goal of providing expert advice on the diagnosis, evaluation, and management of lung disease in…

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Progress Report: MD Anderson Cancer Center Investigator Uncovers New Roles for the A-T Protein in Blood and Brain Cells

Jun 1, 2011 Comments Off on Progress Report: MD Anderson Cancer Center Investigator Uncovers New Roles for the A-T Protein in Blood and Brain Cells
Nov 5 @ 4:01 am

Since the late 1990s, Paul K.Y. Wong, PhD, from the University of Texas MD Anderson Cancer Center has been exploring what goes wrong in blood and brain cells when the A-T protein is missing. Although A-T is not the primary research focus for Dr. Wong, a leading investigator in the…

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NIH Spearheads “NEXT” for Pediatric Neurological Trials

Apr 1, 2011 Comments Off on NIH Spearheads “NEXT” for Pediatric Neurological Trials
Nov 5 @ 4:01 am

Over the last few years, the Children’s Neurobiological Solutions (CNS) Foundation and the A-T Children’s Project (A-TCP) began to realize that a critical gap existed in the path to bringing potential therapies to the clinic for children with neurological di sorders. An organized network of multidisciplinary, well-funded clinicians experienced in…

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