News
A-T Brain Imaging Study Offers Clues for Treatments
In a groundbreaking imaging study just published in the journal Brain, researchers made unexpected discoveries about brain activity that now have them thinking about new treatments that could help people with ataxia-telangiectasia (A-T) control their movements better. Nora Volkow, MD, Director…
moreUnravelling Nerve-cell Death in Rare Children’s Disease
From the Sanford-Burnham Medical Research Institute Press Release: Researchers discover mutations in a protein that plays a role in the body’s DNA repair system—similar to what’s observed in the rare children’s disease ataxia-telangiectasia. The discovery provides an approach to identifying…
moreUnderstanding A-T Through Brain Imaging Technology
Using brain imaging technology, researchers at the University of Nottingham, United Kingdom, are working on a way to develop biomarkers for ataxia-telangiectasia that may enable and accelerate future clinical trials. Biomarkers are indirect measures of the underlying disease process that…
moreOptimizing Cancer Management in A-T
The A-T Children’s Project hosted a small, two-day workshop in Boston, Massachusetts entitled “Optimizing Cancer Management in A-T.” Clinical oncologists and immunologists from around the world gathered to discuss what is known, and what needs to be learned, about caring…
moreA-TCP Leader to Co-chair Neuronext Oversight Board at NIH
Brad Margus has been tapped to co-chair the oversight board for the Network for Excellence in Neuroscience Clinical Trials, or NeuroNEXT, a new, innovative program at the National Institutes of Health. NeuroNEXT, will provide a robust, standardized, and expert network…
moreNew Mouse Model of A-T May Have Neurological Symptoms Similar to Kids With A-T
We have just awarded funding to Margot Mayer-Proschel, PhD at the University of Rochester to characterize a new mouse model that her lab has developed for A-T. Previous A-T mouse models have been useful for studying the biochemical, cancer, and…
moreExamining Circuitry and Possible Inflammation in the A-T Brain
With funding from the A-T Children’s Project and the Australian-based BrAshA-T organization, a team of researchers in Australia is using neuroimaging technology to learn more about abnormal circuitry and inflammation in the brains of A-T patients, possibly providing clues for…
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