Research Grant Program
Research We Support
The A-T Children’s Project supports promising research with sound scientific rationale. No idea is too novel for us to consider, as long as it has clear relevance for people with ataxia telangiectasia (A-T) and the potential to lead to a therapy. We welcome applications from academia and industry scientists, small biotechnology and large pharmaceutical companies, and even from venture capital firms that are incubating new technologies which may hold promise for A-T. Our portfolio spans basic, translational and clinical research.
Open to Ideas
We are open to creative ideas conceived by investigators. From time to time, we also encourage projects that address a specific gap in scientific understanding, patient need or therapeutic development. In addition, we sometimes provide add-on, supplemental funding if a grant we already awarded shows significant progress and continued potential.
Our grants come with more than money. We frequently guide researchers to research tools such as A-T animal models, cell-based assays, patient biospecimens and clinical datasets. We also help grant recipients connect with advisors who have been in the A-T field for a long time and with collaborators whose work may have synergies. A-T researchers may also attend virtual and in-person meetings that we organize.
Our Current Focus
While the A-T Children’s Project has previously granted millions of dollars to support projects aimed at elucidating A-T biology, we are now focusing our limited funds on experiments whose success will provide a clear path to a treatment or intervention for A-T. For example, we are enthusiastic about exploring new DNA-based modalities that may cause a working ATM protein to be produced in the cerebella of people with A-T, or testing compounds that have a strong mechanistic hypothesis for having efficacy in a patient with A-T. We are also eager to support the development of biomarkers and digital tools that could improve and accelerate clinical development for A-T.