width=With support from the A-T Children’s Project, the lab of Sharon McGrath-Morrow, MD, a pediatric pulmonologist for the A-T Clinical Center, is sequencing RNA from A-T patient blood cells in hopes of identifying markers that will correlate with either immune problems or cancer and predict the disease’s course. If found and validated, such biomarkers could allow researchers to confirm proof of mechanism and see efficacy more quickly during clinical trials or potentially treat specific subsets of A-T patients more precisely.

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