Press Kit For more information, please contact Jennifer Thornton, Executive Director at email@example.com. A-T Children's Project Ataxia-telangiectasia (A-T) is a genetic disease that causes loss of muscle control and balance, cancer, lung disease and immune system problems in children & young adults, shortening their lives. The nonprofit A-T Children’s Project partners with academic and industry investigators worldwide – organizing and supporting innovative research, conferences, clinical teams, data platforms and biomarker development – to optimize disease management strategies, develop new treatments and find a cure. Ataxia-Telangiectasia (A-T): Is a rare genetic diseaseAttacks in early childhoodOne in 40,000 – 100,000 babies is born with A-TAffects many body systems including the brain, lungs, and immune system. As such, A-T patients may suffer from symptoms like those seen in cerebral palsy, muscular dystrophy, and certain lung disorders. People with A- T are also much more likely to develop cancer, particularly immune-related cancers such as leukemia and lymphoma. Children with A-T: Both boys and girls of all ethnic backgrounds are affectedMost children with A-T depend on a wheelchair by age 10About 30 percent of children with A-T develop cancersAbout 70 percent of children with A-T have weakened immune systems100 percent of children with A-T experience relentless loss of muscle control due to brain cell death that affects their walking, speech, swallowing, and reading Other Facts: There is currently no cure for A-T and no way to slow the progression of the disease. Parents of A-T children do not exhibit symptoms of the disease, but (usually unknowingly) carry a mutated gene that causes it. Each time two “A-T carriers” have a child together, there is a 1 in 4 chance that child will have A-T. Similarities between A-T and other major diseases suggest knowing more about A-T could lead to therapies for more common diseases such as cancer, Alzheimer’s, and Parkinson’s. Ataxia Telangiectasia Children's Project Our organization:Encourages and supports laboratory research to accelerate the discovery of a cure or possible therapies for A-T by:Awarding competitive research grants to top scientists using a peer-review board of scientific expertsSponsoring workshops and symposia to encourage cooperation among laboratories and generate new research strategiesWorking with Congress and the National Institutes of Health to encourage U.S. government funding of active research on A-TFunds a multi-disciplinary, international center at Johns Hopkins Hospital in Baltimore, Maryland to focus solely on the clinical evaluation and treatment of patients with A-T.Improves the accurate and timely diagnosis of A-T patients by increasing public awareness and educating physicians.Maintains an international registry of A-T patients and tissue/cell banks to provide up-to-date clinical information and resources to researchers.Provides emotional encouragement, guidance, and hope to families impacted by A-T through telephone support, an internet forum, and family conferences.